Heart Rate Variability

Dr. Lin Yu-Hsuan and the research team have focused on the study of Heart Rate Variability (HRV) for many years, exploring its diverse applications in medical and social health issues.

HRV is a measure derived from analyzing continuous heart rate variations using time-domain, frequency-domain, and non-linear mathematical models. It quantifies sympathetic and parasympathetic nervous system functions and holds significant clinical value. HRV not only predicts cardiovascular disease risks but also reflects autonomic nervous system activity.

Our team’s research spans various fields, including the impact of mental stress on myocardial ischemia and cardiovascular events in patients with coronary heart disease, the effects of shift work and long working hours on the physiological functions of healthcare workers, the influence of treatments such as methadone therapy on autonomic function in heroin-dependent individuals, and the effects of aging and congestive heart failure on HRV.

Our research team has demonstrated HRV’s value in psychiatry, psychophysiology, and workplace health, emphasizing the connections between gender differences, autonomic regulation, and personality traits. Additionally, they have explored the role of HRV in the use of psychotropic medications (such as antipsychotics and anticholinergic drugs) and applied HRV to evaluate health-related quality of life and health management strategies for patients with mental disorders.

Through these groundbreaking studies, the team has provided significant insights into HRV’s role in cultural and medical practices, while advancing its use as a diagnostic tool and health indicator in a wide range of applications.

Publications

1. Cultural resonance and medical practice: Heart rate variability test in Taiwanese psychiatry clinics.


Lin YH, Chen TY
Journal of psychosomatic research. 2024 Sep:184:111860.

Listen to the audio summary of a paper produced by Google NotebookLM.

2. Mental Stress–Induced Myocardial Ischemia and Cardiovascular Events in Patients With Coronary Heart Disease


Lin YH.
JAMA.2022 Mar 15;327(11):1091.

 Listen to the audio summary of a paper produced by Google NotebookLM.

3. Cardiac Autonomic Modulation during on-Call Duty under Working Hours Restriction.


Chien JW, Chen CY, Lin SH, Lin SW, Lin YH.
International Journal of Environmental Research and Public Health. 2020 Feb 10;17(3).
Listen to the audio summary of a paper produced by Google NotebookLM.

4. Viral Infection, Psychopathology, and Autonomic Modulation Among Methadone Users in Taiwan.


Huang WL, Chang LR, Kuo TBJ, Lin YH, Yang JL, Chen YZ, Yang CCH.
Heroin Addiction and Related Clinical Problems. 2017;19(6):31-38.

5. Novel Application of Multi Dynamic Trend Analysis as a Sensitive Tool for Detecting the Effects of Aging and Congestive Heart Failure on Heart Rate Variability.


Lin YC, Lin YH, Lo MT, Peng CK, Huang NE, Yang CC, Kuo TB.

Chaos: An Interdisciplinary Journal of Nonlinear Science. 2016 Feb;26(2):023109.
Listen to the audio summary of a paper produced by Google NotebookLM.

6. Impact of Antipsychotics and Anticholinergics on Autonomic Modulation in Patients with Schizophrenia.


Huang WL, Chang LR, Kuo TB, Lin YH, Chen YZ, Yang CC.

Journal of Clinical Psychopharmacology. 2013 Apr;33(2):170-7.
Listen to the audio summary of a paper produced by Google NotebookLM.

7. Gender Differences in Personality and Heart-Rate Variability.


Huang WL, Chang LR, Kuo TB, Lin YH, Chen YZ, Yang CC.

Psychiatry Research. 2013 Oct 30;209(3):652-7.
Listen to the audio summary of a paper produced by Google NotebookLM.

8. Gender Differences in Cardiac Autonomic Modulation During Medical Internship.


Lin YH, Chen CY, Lin SH, Liu CH, Weng WH, Kuo TB, Yang CC.

Psychophysiology. 2013 Jun;50(6):521-7.
Listen to the audio summary of a paper produced by Google NotebookLM.

9. On-call Duty Effects on Sleep-State Physiological Stability in Male Medical Interns.


Lin YH, Ho YC, Lin SH, Yeh YH, Liu CY, Kuo TB, Yang CC, Yang AC.

PloS one. 2013 Jun 4;8(6):e65072.
Listen to the audio summary of a paper produced by Google NotebookLM.

10. Methadone-Mediated Autonomic Functioning of Male Patients with Heroin Dependence: the Influence of Borderline Personality Pattern.


Huang WL, Lin YH, Kuo TB, Chang LR, Chen YZ, Yang CC.

PLoS One. 2012;7(5):e37464.
Listen to the audio summary of a paper produced by Google NotebookLM.

11. Cardiac Autonomic Modulation During Methadone Therapy Among Heroin Users: a Pilot Study.


Chang LR, Lin YH, Kuo TB, Ho YC, Chen SH, Wu Chang HC, Liu CM, Yang CC.

Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2012 Apr 27;37(1):188-93.
Listen to the audio summary of a paper produced by Google NotebookLM.

12. Autonomic Modulation and Health-Related Quality of Life among Schizophrenic Patients Treated with Non-Intensive Case Management.


Chang LR, Lin YH, Kuo TB, Wu Chang HC, Liu CM, Liu CC, Hwu HG, Yang CC.

PLoS One. 2011;6(11):e26378.
Listen to the audio summary of a paper produced by Google NotebookLM.