Sleep Medicine

The 2017 Nobel Prize in Physiology or medicine Winning Theme “Controlling the molecular mechanisms for circadian rhythm ”, pointed out that irregular sleep patterns may increase the risk of psychiatric and medical illnesses. For academia and clinicians, there is difficulty in long -term (months or years) naturalistic and objective recording of daily sleep patterns. We have developed a smartphone -based automatic sleep recording system– “Rhythm ” which successfully solves this barrier to research.


1. Increased Internet Searches for Insomnia as an Indicator of Global Mental Health During the COVID-19 Pandemic: Multinational Longitudinal Study.

Lin YH, Chiang TW, Lin YL. J Med Internet Res. 2020 Sep 21;22(9):e22181. doi: 10.2196/22181. PMID: 32924951.

2. Validation of the Mobile App-Recorded Circadian Rhythm by a Digital Footprint.

Lin YH, Wong BY, Pan YC, Chiu YC, Lee YH. JMIR Mhealth Uhealth. 2019 May 16;7(5):e13421. Do you have social jet lag?

3. Development of a mobile application (App) to delineate “digital chronotype” and the effects of delayed chronotype by bedtime smartphone use.

Lin YH, Wong BY, Lin SH, Chiu YC, Pan YC, Lee YH. Journal of Psychiatric Research. 2019 Mar;110:9-15. Does using a smartphone before bed affect sleep patterns?

4. Association between morningness–eveningness and the severity of compulsive Internet use: the moderating role of gender and parenting style.

Lin YH, Gau SS. Sleep Med. 2013 Dec;14(12):1398-404.doi:10.1016/j.sleep.2013.06.015.Epub 2013 Sep 12.

5. On-call duty effects on sleep-state physiological stability in male medical interns.

Lin YH, Ho YC, Lin SH, Yeh YH, Liu CY, Kuo TB, Yang CC, Yang AC. PloS one. 2013 Jun 4;8(6):e65072.

6. Polysomnography in Kleine-Levin syndrome.

Huang YS, Lin YH, Guilleminault C. Neurology. 2008 Mar 4;70(10):795-801.
NHRI Digital Biomarkers Lab
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